Diacerin 13739-02-1

Availability: In Stock
CAS NO.: 13739-02-1
M.F.: C19H12O8
M.W: 368.29



Product name Diacerin
CAS NO. 13739-02-1
M.F. C19H12O8
M.W 368.29
Structure 4
EINECS 237-310-2
Chemical Properties
Melting point 217-218 °C
Density 1.491g/cm3
Boiling point 631.5°C at 760 mmHg
Flash point 231.8°C
Diacerin Package
Net weight 25kgs
Gross weight 27.5kgs
Certificate GMP factory, GMP


Appearance Yellow crystalline solid
Assay 98.0-102.0%
Loss on drying NMT 0.5%
PH 4.5-6.0
Residue on ignition NMT 0.20%
Heavy metals NMT 20ppm
Related substances Any single impurity not more than 0.5%
Total impurities not more than 1.0%


This product is the primary inhibitor of IL-1 in osteoarthritis.Confirmed by cell and animal experiments:

(1) This product can induce chondrogenesis and has analgesic, anti-inflammatory and antipyretic effects;

(2) Do not inhibit prostaglandin and prostaglandin;

(3) Osteoarthritis has the effect of delaying disease progression;

(4) Repress the production of metalloproteinases and peroxides such as collagenase and stromal lysin;

(5) Promote the synthesis of collagen and aminoglycan;

(6) Inhibit the chemotaxis of leukocytes and stabilize lysosomes.At present, this drug is mainly used for the treatment of osteoarthritis, rheumatoid arthritis is likely to have a therapeutic effect.

First aid measures

4.1 Description of necessary first aid measures

General advice

Consult a doctor.Show this safety specification to the on-site doctor.

If inhaled

If inhaled, remove to fresh air.If you stop breathing, give artificial respiration.Consult a doctor.

In the case of skin contact

Rinse with soap and plenty of water.Consult a doctor.

In the case of eye contact

Flush thoroughly with plenty of water for at least 15 minutes and consult your doctor.

If the mistake

Never feed an unconscious person anything from his mouth.Rinse your mouth with water.Consult a doctor.

4.2 Most important symptoms and effects, acute and delayed

Rash, diarrhea, upper abdominal pain, to our knowledge, the chemical, physical, and toxic properties have not been fully studied.

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