(2R,3S)-2-{(1R)-1-[3,5-Bis(Trifluoromethyl)Phenyl]Ethoxy}-3-(4-Fluorophenyl)Morpholine Hydrochloride 171482-05-6

Availability: In Stock
CAS NO.: 171482-05-6
M.F.: C20H19ClF7NO2
M.W: 473.81200

Description

BASIC INFORMATION

Product name (2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl) morpholine hydrochloride
Other name (2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl) morpholine,hydrochloride
CAS NO. 171482-05-6
M.F. C20H19ClF7NO2
M.W 473.81200
Structure 1
EINECS 1308068-626-2
Chemical Properties
Melting point 108-110℃
Density 1.83
Boiling point 387.9 °C at 760 mmHg
Flash point 188.4ºC
Safety information
Not dangerous goods
Storage: Closed tight; stored in dry place; avoid sunlight.
Package
Net weight: 25 kgs/drum

Specification

PRODUCT NAME (2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl) phenyl) ethoxy)-3-(4-fluorophenyl) morpholine hydrochloride CAS NO171482-05-6
ITEM specification RESULT
CHARACTER WHITE OR OFF WHITE CRYSTALLINE POWDER CONFORM
WATER ≤1.0% 0.1%
Enantiomer AR-1(SRS)NMT0.1% ND
RELATED SUBSTANCE AR-1(RRS) NMT 0.20% ND
AR-1(RSS) NMT 0.20% ND
AR-1(RRR) NMT 0.20% ND
Single impurity NMT 0.20% 0.08%
TOTAL IMPURITIES NMT1.0% 0.1%
ASSAY ≥99.0% 99.9%
STORAGE CLOSED, IN COOL PLACE(3~8℃)
CONCLUSION COMFORM TO THE STANDARD

USAGE

(2R,3S)-2-((R)-1-(3,5-Bis(trifluoromethyl) phenyl) ethoxy)-3-(4-fluorophenyl) morpholine hydrochloride is used as intermediate of Fosaprepitant dimeglumin and Aprepitant.

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